If this happens, you may get confused, disoriented, or have difficulty thinking. Carbonic anhydrase inhibitors, including acetazolamide, dichlorphenamide, methazolamide, and dorzolamide, increase the risk of kidney stones when taken with topiramate. It is very important to tell your doctor how you feel things are going during the first few weeks after you start taking topiramate. It will probably take several weeks to see big enough changes in your symptoms to decide if topiramate is the right medication for you.
Mood stabilizer treatment is generally needed lifelong for persons with bipolar disorder. Your doctor can best discuss the duration of treatment you need based on your symptoms and course of illness.
Last Updated: January This information is being provided as a community outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes only and is not medical advice.
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I Accept Show Purposes. Let's face it: Not all weight loss therapies work for all people. Each of us has a different genetic composition and a different reason for weight gain.
Other factors include: It's not targeted to your weight gain - See above. Other common causes of weight gain include: insulin resistance, leptin resistance , binge eating disorder, menopause, thyroid disease and so on. You are not using the right dose - This usually isn't a problem but it's worth considering.
We will discuss dosing below. There are better medications available to you - Not everyone will do well on Topamax and that's ok. Listen to your body and don't take the medication just because you really want it to work. You aren't combining it with a healthy diet or with exercise - No matter which weight loss medication you use you should always combine it with a healthy diet and exercise.
Using weight loss medications by themselves often does not work. You haven't been using it long enough 10 - Weight loss should NOT be extreme and occur over a period of a few weeks.
Long lasting weight loss often takes months and months to achieve. Topamax may take weeks to kick in then months after that for more weight loss.
Side effects of the medication may be causing weight gain - Some weight loss medications can paradoxically cause weight gain instead of weight loss. Topamax Dosage The goal with dosing is to achieve a balance between dose and results. Side Effects While Topamax may be effective for weight loss it doesn't come without cost. You can see a long list of potential side effects of Topamax below: Fatigue Drowsiness Diarrhea Nausea Brain fog Slow thinking or poor cognition Memory problems Dizziness Flu-like symptoms The good news is that many of these symptoms tend to be dose-related, meaning the higher your dose the more likely you are to experience them.
And you may be right in that logic. Qsymia is a medication which has already done just that. This dose can be increased up to 15mg of Phentermine and 92mg of Topiramate.
The same may also be potentially true for combining Wellbutrin with Topamax. Because of this, it's important for you to know all available options. Phentermine - This medication is an appetite suppressant and also may help boost metabolism. Wellbutrin - Wellbutrin works in a variety of ways and may help people with certain conditions. LDN low dose naltrexone - LDN can help reduce inflammation and help with weight loss, especially in those with autoimmune diseases.
Qsymia - Discussed in this article T3 thyroid hormone - T3 is the active thyroid hormone and can help boost metabolism in those with thyroid disease.
Testosterone - Testosterone can be used by itself to help increase muscle mass which may help improve metabolism.
Metformin - Metformin helps regulate insulin resistance and can be combined with other medications for weight loss. Conclusion Topamax is a medication which can potentially help with weight loss. That being said, it's not for everyone. This medication carries with it some serious side effects that should not be ignored. Now I want to hear from you: Have you used Topamax for weight loss? There are no known interactions between Topiramate and lithium. However, carbamazepine can lower the blood-plasma level of Topiramate by 50 percent and valproate can lower it by 15 percent.
Topiramate itself can lower the blood-plasma level of valproate by 10 percent. Thus far, there are no known interactions for patients taking Topiramate and either lamotrigine or gabapentin. The final doses of Topiramate vary widely based on the targeted disorder, the patient, and whether or not the patient is taking any other drugs at the same time. The most common doses fall between 50 and mg a day for most therapies, but this can be lower for PTSD.
Higher final doses may be required if Topiramate is being taken alone, up to mg a day. Some patients experience relief with only 25 mg a day.
This also varies significantly depending on the individual. Some feel the effects within days, while others need up to a month before they feel any difference. The five side effects that were most likely to cause people to discontinue use of Topiramate were psychomotor slowing, fatigue, memory problems, confusion, and somnolence.
In rare cases, approximately one person of patients develop kidney stones and a very few develop acute glaucoma. The list includes sedation, psychomotor slowing, agitation, anxiety, concentration problems, forgetfulness, confusion, depression, and depersonalization. There are also rare cases of psychosis. The interactions between Topiramate, valproate, and carbamazepine have already been noted above.
In addition to that, Topiramate appears to raise the blood-plasma level of phenytoin, while phenytoin decreases the level of Topiramate by 50 percent. There have been some reports that Topiramate reduces the effectiveness of oral contraceptive pills.
That means the drug is known to affect the human fetus in an adverse way, but there is not much research about the specifics, and that the drugs benefits may outweigh the risks. So far, there are no reports about using Topiramate for older adults, although there is no reason to believe that they would have a different response to it. There are no reports of bad reactions to suddenly stopping use of Topiramate, so there is no need to wean off the drug.
On the other hand, the entire class of anticonvulsants is known to lead to seizures if you stop taking them suddenly. Therefore, the only thing that should lead to a sudden cessation of Topiramate use is the rise of a dangerous side-effect. When bought in bulk, Topiramate is not particularly expensive.
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